Human Herpes Virus 6
- epidemiology
- classification and characteristics
- transmission and infection
- pathogenicity and virulence
- clinical manifestations
- diagnosis
- treatment
Human Herpes Virus 6 (HHV6) is the causative agent in roseola.
Epidemiology
Roseola typically affects children under 3.
Classification and Characteristics
Transmission and Infection
Incubation period is typically 5-15 days. Infection patterns are not known.
Pathogenicity and Virulence
Clinical Manifesations
Patients develop a high fever lasting 3-5 days, along with:
- cough
- nasal congestion
- erythematous pharynx, tonsils, TM
- cervical lymphadenopathy
- bulging anterior fontanelle if CNS involvement
- rash appears after fever ends: pink, non-pruritic macules and papules which coalesce and disappear within 1-2 days
Complications include febrile seizures and encephalitis.
Diagnosis
Treatment
Treatment is supportive, including acetaminophen.