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Muskuloskeletal injuries, conditions, and diseases are extremely common.
Shoulder
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Hipslipped capital femoral epiphysis
Anklelateral sprain medial sprain |
buckle, greenstick, plastic deformation
growth plate injury - fracture of cartilage cells in hypertrophic zone. heals well and rapidly, often faster than bone.
distal radius is the most common
four main types
type I - straight across
type II - within cartilage and into metaphysis
type III - from growth plate into proliferative zone
type IV - from growth plate into both epiphysis and metaphysis
injury can negatively affect growth by stimulating too much or not enough.
Autoimmune Connective Tissue Disorders
Characterized by autoimmunity against systemic proteins and multi-system disease, often associated with constitutional symptoms.
Heritable Connective Tissue Disorders
Tumours of the musculoskeletal system can range from the more common benign to the rarer malignant tumours. While they can arise from any cellular element, they are almost always mesenchymal in origin.
In general, sarcomas tend to arise de novo, not from benign neoplasms. Many preferentially affect children and young adults. Many sarcomas have characteristic molecular abnormalities, especially chromosomal translocations, though the ultimate etiology of most is unknown.
bone tumours osteoma and osteosarcoma chondroma and chondrosarcoma Ewing's sarcoma |
soft tissue tumours Soft tissue tumours arise anywhere deep to the skin and above the periosteum.
fibroma and fibrosarcoma lipoma and liposarcoma leiomyoma and leiomyosarcoma rhabdomyoma and rhabdomyosarcoma angioma and angiosarcoma
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Most sarcomas are high grade, with a moderate to high rate of metastatic spread via the blood. The lung is the most frequent site of metastasis.
An enlarging mass is the most common symptom of soft tissue tumours.
Pain is the most common symptom of bone tumours. The pain is persistent and of increasing intensity, not associated with a history of trauma. They may present with pathologic fracture.
Bone may respond via lysis, remodeling, or mixed lysis and remodeling.
Psuedotumours are conditions that simulate true neoplasms