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Polycythemia
C
- signs and symptoms
- types of polycythemia
- diagnosis
- pathophysiology
- causes and risk factors
- treatments
- course
Signs and Symptoms
- essential thrombocytosis
- myelofibrosis
- myeloid metaplasia
Types of Polycythemia
Primary polycythemia is a clonal myeloproliferative disease
Secondary polycythemia is non-clonal and is caused by, for example increased EPO.
False polycythemia is caused by a decrease in plasma volume (dehydration, diuretics, etc)
Diagnosis
Pathophysiology
- A mutation in JAK-2 is seen in 65-97% of patients
Causes and Risk Factors
Treatments
Course
Can go into hibernation, or can also progress into AML.