Estrogen

Estrogen is a key reproductive hormone.

 

Function

Estrogen initiates female pubertal development, including breat development, widening of the pelvis, and distribution of body fat.

 

Together with progesterone, estrogen regulates the menstrual cycle.

 

plasma estradiol levels during the menstrual cycle

phase

  • early follicular
  • late follicular
  • ovulatory
  • early/mid luteal
  • late luteal

plasma levels (pmol/L)

  • 75-600
  • 110-1500
  • 170-1000
  • 75-1000
  • 10-900

Regulation of Expression

FSH, released from the anterior pituitary, acts on granulosa cells in the ovary, inducing their production of estrogen.

 

 

 

 

 

Consequences of Overexpression

 

 

Consequences of Underexpression

 

 

Signalling Pathways

 

 

Structure