The clinical exam assessing for kidney disease is very important, as kidney disease often goes undiagnosed.
Prescription and over-the counter drugs, street drugs, herbs can also lead to acute or chronic interstitial nephritis.
Diabetes and/or hypertension, along with other complications such as retinopathy or neuropathy, can suggest the cause of kidney disease.
Recurrent urinary tract infections can cause reflux nephropathy.
Recurrent renal calculi can result in chronic obstruction.
Systemic disorders:
Alport's syndrome
Retina: look for signs of diabetes, hypertension, bacterial endocarditis, and cholesterol emboli
Skin: look for presence of edema, rash, and purpura. Assess sacral edema if patient is supine.
Joints: signs of arthritis
Rectal/pelvic exam to exclude protstate/gynecological causes of urinary obstruction
Assessing volume status is critical in nephrology. Look for:
Dehydration in infants and children