Depression During Pregnancy

 

 

Causes and Risk Factors

 

 

 

 

 

Signs, Symptoms, and Diagnosis

 

 

 

 

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Pathophysiology

 

 

 

 

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Treatments

 

Support - partner, family, friends, RN, MSW, MD, prenatal classes, exercise program.

 

Motherrisk offer advice regarding pharmacotherapy

Exposure through placenta, amniotic fluid, and lactation

 

Medications

SSRIs show no increase in miscarriage and no teratogenicity; no adverse effects on cognition, language, or temperament up to 2006. Possible low birth weight and moderate premature delivery.

20-30% of newborns exposed during the 3rd trimester develop neonatal adaptation syndrome - transient, mild, increa:sed crying and feeding problems).

JAMA 2006 - persistent pumonary hypertension of the newborn. Risk increases from 1-2 to 6-12/1000; 99.5% of children are ok.

CVS abnormality with paroxetine: risk increases from 1:100 to 1:50.

Pros and cons; treat in warranted.

Other medications include: TCAs (desipramine, nortryptiline), venlafaxine, bupoprion; avoid MAOIs.

 

 

ECT can safely be used as lifesaving treatment during pregnancy.

 

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Consequences and Course

 

 

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The Patient

 

 

 

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Health Care Team

 

 

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Community Involvement

 

 

 

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References