Ghrelin

Norepinephrine (NE)

 

Function

Ghrelin is an endogenous ligand of growth hormone secretagogue receptor in the pituitary and hypothalamus. It is released during periods of fasting to increase GH secretion.

 

It also acts on the liver to...

 

Regulation of Expression

Ghrelin is produced by gastric neuroendocrine cells.

 

Consequences of Overexpression

Overexpression of PRL (hyperprolactinemia) can lead to galactorrhea

 

Consequences of Underexpression

 

 

Signalling Pathways

Both PRL and GH have similiar affinities for the PRL receptor.

 

Structure

Prolactin is a 199 amino acid hormone with 16% homology to growth hormone.