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Chloramphenicol
bacteriostatic antibacterial drug
- uses
- mechanism
- dose and half-life
- adverse drug reactions
- counter-indications and drug interactions
- metabolism and excretion
- dependency
Uses
- drug of choice only for Typhoid fever due to serious risk of aplastic anemia
- wide range of gram-negative and -positive bacteria
- active against Rickettsia, Chlamydia, Mycoplasma
Mechanism
- inhibits protein synthesis by binding the 50S ribosomal subunit
Dose and Half Life
Adverse Drug Reactions
- can cause aplastic anemia
Counter-Indications and Drug Interactions
Metabolism and Excretion