Topoisomerase II
DNA-associated enzyme that is associated with double-stranded break repair
Introduction
Function
Expression
- cells that express:
- tissue distribution:
- temporal expression:
Interactions and Signalling
Drugs that Target
- Topoisomerase II inhibitors such as etoposide are active late in the cell cycle and used as anti-cancer agents
Role in Disease
Structure
Gene and Processing
- PubMed ref: here
- other info