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A solitary pulmonary nodule is a spherical lesion less than 3 cm in the lung.
Depending on the population, up to 50% are malignant. This is clearly high enough to warrant investigation, though not to automatically lead to resection.
Benign nodules can be infectious granulomas (histoplasmosis), noninfectious granulomas, hamartomas, and other benign tumours.
Act quickly. If malignancy is suspected, surgical resection should be done. Needle biopsy can be done if surgical contraindications exist, though they are not completely sensitive.
Comparison with previous images can be useful to determine change, or lack thereof. Smooth edges and calcification suggest benign. CT or PET scans can also be useful.
PET can be used if available.
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