page sections

Joint Pain

 

 

 

Causes of a Painful, Swollen Joint

 

  • infectious
  • inflammatory
  • connective tissue disease
  • neoplastic
  • vasculitis
  • bleeding
  • bone

Infectious

 

Septic infection

  • Staph
  • Strep
  • H. influenza (in unimmunized)
  • Gonorrhea

Viral infection (less common; a presumed virus of exclusion)

 

Fungal: especially in immunocompromised patients, or with direct puncture

 

TB

 

lyme disease

Reactive arthritis

  • Shigella
  • Samonella
  • Campylobacter
  • Yersinia
  • Gonorrhea (septic or reactive)
  • Chlamydia
  • Streptococcus

Inflammatory

 

Juvenile inflammatory arthritis

  • oligo-articular
  • polyarticular (RF -ve or +ve)
  • systemic
  • enthesitis-related
  • psoriatic

Connective Tissue Disease

 

systemic lupus erythmatosis

dermatomyositis

mixed connective tissue disease

Neoplastic

Important to address this possibility for parents

  • leukemia
  • lymphoma
  • neuroblastoma (in children)

 

Benign or maligant

  • oseoid osteoma
  • osteosarcoma
  • Ewing's sarcoma
  • chondroma
  • chondrosarcoma
  • synovial sarcoma
  • rhabdomyoma
  • rhabdomyosarcoma

Vasculitis

 

Bleeding

 

Bone

Osteomyelitis

Mechanical or orthopedic

 

 

Signs, Symptoms, and Diagonsis

  • history
  • physical exam
  • lab investigations
  • diagnostic imaging

History

questions about joint pain

morning stiffness -

effect of activity

time of day

which joints are affected?

 

 

extra-articular symptoms

fatigue, fever, weight loss, night sweats

respiratory: shortness of breath, chest pain

skin:

look for pitting in the nails in psoriatic arthritis.

 

functional

self-care

cooking

dressing

distance walking

stairs

 

past medical history

  • sexually transmitted infections
  • URTI (transient synovitis)

Physical Exam

 

On physical examination, active and passive range of motion should be assessed, and the presence of tenderness, swelling, warmth, erythema, deformity, and effusions should be evaluated.

Range of Motion

A good quantifier of joint inflammation is grip strength.

Lab Investigations

CBC

ESR, CRP

blood culture

 

 

Diagnostic Imaging

 

X-ray

Bone scan or MRI, depending on institution