Infectious
Septic infection
Viral infection (less common; a presumed virus of exclusion)
Fungal: especially in immunocompromised patients, or with direct puncture
TB
lyme disease
Reactive arthritis
Juvenile inflammatory arthritis
systemic lupus erythmatosis
dermatomyositis
mixed connective tissue disease
Important to address this possibility for parents
Benign or maligant
Osteomyelitis
Mechanical or orthopedic
morning stiffness -
effect of activity
time of day
which joints are affected?
fatigue, fever, weight loss, night sweats
respiratory: shortness of breath, chest pain
skin:
look for pitting in the nails in psoriatic arthritis.
self-care
cooking
dressing
distance walking
stairs
past medical history
On physical examination, active and passive range of motion should be assessed, and the presence of tenderness, swelling, warmth, erythema, deformity, and effusions should be evaluated.
A good quantifier of joint inflammation is grip strength.
CBC
ESR, CRP
blood culture
X-ray
Bone scan or MRI, depending on institution