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Immune Response to Fungal Infection
The immune response to fungi depends largely on phagocytosis.
Giardia attachment is blocked by IgA
Trympanosomes are attacked by antibodies, complement, and frustrated phagocytosis. However, Most of the immune response is against the surface coat of variable surface glycoprotein. Periodic gene rearrangement and coat shedding leads to episodic disease.
Leishmania lives inside macrophages, and IFN-gamma induces increased ROS and RNS production.
Malaria is not dealt with well by the immune system.
Schistosomes live in the portal system and induce eosinophil granulomas and IgE production. It appears that a Th2 response instead of a Th1 response is a plan by the worm to survive
Nematodes