Rh Disease

 

Prevention is more important

can inject anti-Rh immunoglobin

inject at 28 weeks, booster at 34 weeks

  • reduces rate to .1% from 7% for 1st birth
  • reduces rate to 1.3% from 13% for 2e birth

 

 

 

0.1 ml = 3%

5 ml = 60%

 

do titres at 12-16 weeks, 28-32 weeks, and close to delivery

1:64 titres represent a threshold of antibody levels necessitating further investigations in the baby, such as amnicentesis looking for bilirubin.

 

They usually induce 2-5 weeks early.

 

 

 

 

Can do exchange transfusions if absolutely necessary

take out 10-20 ml, add O-ve back in

 

 

 

test all babies with Coomb's test and bilirubin in core blood as a screening test.