Oral Rehydration Therapy

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Introduction

Oral rehydration therapy (ORT) was first introduced in 1979 and rapidly became a key tool in the control of death from diarrheal illnesses.

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Reduced osmolarity formulation is associated with less diarrhea, vomiting, and need for IV hydration in children with diarrhea, compared to standard osmolarity solution (Hahn, Kim, and Garner, 2001).

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molecule

grams/litre

ion

mmol/litre

sodium chloride

2.6

sodium

75

glucose

13.5

chloride

65

potassium chloride

1.5

glucose

75

trisodium citrate, dihydrate

2.9

potassium

20

 

 

citrate

10

 

 

total osmolarity

245

 

 

 

Resources and References

Hahn S, Kim Y, Garner P. 2001. Reduced osmolarity oral rehydration solution for treating dehydration due to diarrhoea in children: systematic review. BMJ. 323(7304):81-5.

Victora CG et al. 2000. Reducing deaths from diarrhoea through oral rehydration therapy. Bull World Health Organ. 78(10):1246-55.

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