Mesenteric Ischemia
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Introduction
The Case of...
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Causes and Risk Factors
There are four main causes of mesenteric ischemia:
- arterial embolism
- arterial thrombosis
- nonocclusive
- venous thrombosis
Risk factors include:
- atherosclerosis
- recent myocardial infarction
- arrhythmia, such as atrial fibrillation
- hypercoagulability
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Pathophysiology
Inferior mesenteric artery (IMA) is often the first to go, as it is lower down and can become involved in aortoiliac disease.
It can also be tied off during surgery, with little initial consequences.
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Signs and Symptoms
History
Symptoms are typically:
- a rapidly developing, severe, steady periumbilical pain
- postprandial abdominal pain
- nausea and vomiting
- association with forceful bowel movement
Chronic symptoms can include:
- weight loss
- food avoidance
- grumbling pain
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Investigations
- lab investigations
- diagnostic imaging
Lab Investigations
Diagnostic Imaging
Plain film and CT scan can show bowel wall thickening or pneumatosis intestinalis.
Mesenteric angiography is the most helpful, but is often unavailable. Often two vessels are occluded and the other stenosed.
Colonoscopy and doppler ultrasound is typically negative and therefore not helpful.
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Differential Diagnosis
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Treatments
Minimally invasive, endovascular approaches can be taken by interventional radiologists or vascular surgeons.
- simple, decreased hospital stay
- good for salvage situations
- higher rates of restenosis
Open repair
- more durable and with higher clinical success
- longer length of stay
- more risk of complications
- diarrhea can be disastrous if approaching anteriorly due to disruption of the celiac plexus
- retrograde approach can be valuable for avoiding complications, traveling alongside the 11th rib.
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Consequences and Course
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Resources and References
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Topic Development
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