Hyperaldosteronism

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Introduction

Probably most common cause of secondary hypertension

 

 

The Case of...

a simple case introducing clincial presentation and calling for a differential diagnosis to get students thinking.

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Causes and Risk Factors

 

Conn's syndrome (tumour)

bilateral adrenal hyperplasia

solitary adenoma

 

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Pathophysiology

 

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Signs and Symptoms

  • history
  • physical exam

History

Physical Exam

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Investigations

  • lab investigations
  • diagnostic imaging

Lab Investigations

K may be normal in 60% of people

Profound hypokalemia in people on diuretic, despite ACEi or ARb

 

Aldosterone/renin ratio (stop spironolactone, beta blocker prior to test)

abnormal response to Na loading

adrenal vein sampling

Diagnostic Imaging

CT or MRI

Often diagnosed incidentally on CT

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Differential Diagnosis

 

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Treatments

 

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Consequences and Course

 

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The Patient

 

 

 

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Health Care Team

 

 

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Community Involvement

 

 

 

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Resources and References

 

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Topic Development

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