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Interleukin-8 (gene name)

IL-8 is a powerful chemotactic factor for neutrophils

• Expression
• Function
• Interactions and Signalling
• Role in Disease
• Structure
• Gene and Processing

Expression

• Macrophages and endothelial cells produce IL-8 in response to IL-1, TNF, or bacterial products

Function

• activates neutrophils and induces their margination and extravasation

Interactions and Signalling

• receptor:

Role in Disease

• if any

Structure

• template

Gene and Processing

• PubMed ref: here
• other info