Polycythemia

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Introduction

• essential thrombocytosis
• myelofibrosis
• myeloid metaplasia

 

 

 

The Case of...

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Differential Diagnosis

Primary polycythemia is a clonal myeloproliferative disease

 

Secondary polycythemia is non-clonal and is caused by, for example increased EPO.

 

False polycythemia is caused by a decrease in plasma volume (dehydration, diuretics, etc)

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History and Physical Exam

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Investigations

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Management

Can go into hibernation, or can also progress into AML.

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Pathophysiology

A mutation in JAK-2 is seen in 65-97% of patients

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Resources and References

 

 

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Topic Development

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