last authored: Oct 2009, David LaPierre
A murmur is an unusual sound generated by turbulent blood flow, resulting from hemodynamic or structural changes to the cardiovascular system. They can become audible or accentuated in high-output states, ie fever or anemia.
courtesy of wikipedia, MadHero88
They are not always a sign of disease, and 50-80% of children will have a murmur at some point.
Murmurs can also suggest structural or functional problems with the heart. Red flags include cardiovascular symptoms, diastolic, pansystolic or continuous murmurs fixed split or single S2, extra sounds, or no change with position.
Murmurs can be caused by various mechanisms:
Knowing WHERE to listen to heart sounds is very important.
Pitch increases with pressure gradient.
Murmurs can be described by volume, pitch, shape, location, radiation, and response to maneuvers.
Innocent murmurs have no associated structural problems or ECG/radiological findings.
timing - all innocent are systolic
less than or equal to 3/6
normal physiological split
no extra sounds
radiation to neck or back
they get better with a change in position - "if it goes away, so does the patient"
breath sounds vs murmur?
Innocent murmurs include:
Systolic murmurs are graded out of 6, while diastolic murmurs are out of 4.
I: very faint
II: soft
III: moderate
IV: loud, with palpable thrill (ie, a tremor or vibration felt on palpation)
V: very loud, with thrill; may be heard when stethoscope is partly off the chest
VI: very loud, with thrill; may be heard with stethoscope entirely off the chest
diamond shaped - crescendo-decrescendo.
The later the peak in volume, the worse it is.
Innocent murmurs are by far the most common. These often disappear when the person sits upright.
Pansystolic, or holosystolic, murmurs, are caused by regurgitation of blood or through a ventricular septal defect. There is uniform sound intensity throughout systole.
There is no isovolemic contraction, as flow starts immediately.
Early murmurs result from regurgitant flow through either the aortic or pulomary valve
aordic regurgitation
pulmonary regurgitation
mitral or tricuspid stenosis
hyperdynamic states such as fever, anemia, hyperthyroidism, and exercise can cause increased flow across normal mitral/tricuspid valves and cause a diastolic murmur.
Continuous murmurs are heard throughout the cardiac cycle and result from conditions where there is a persistent pressure gradient. It is defined as continuing through S2.
venous hums
Fixed S2 Split: Atrial Septal Defect
weak/no femorals: coarctation
murmur quieter when sitting (vs lying down): likely normal (innocent)
down syndrome: atrioventricular canal defect
Turner syndrome: coarctation of aorta
DiGeorge Syndrome: Tetrology of Fallot
Dal