Molar Pregnancy

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Introduction

Molar pregnancies occur in 1:400-2000 pregnancies.

A molar pregnancy, or hyadiform mole, is a trophoblastic neoplasm.

A partial mole has 69 chormosomes from both parents.

A complete mole is an empty egg fertilized by 2 sperm, with all genetic material derived from the father.

a simple case introducing clincial presentation and calling for a differential diagnosis to get students thinking.

Any pregnancy can result in molar pregnancy.

Partial moles are more common with older women becoming pregnant.

Too much beta-hCG leads to hyperemeisis

Exam shows uterus > dates

beta hCG is a perfect tumour marker.

Ultrasound is required for evaluation.

Single agent chemotherapy, ie methotrexate, can be extremely effective in curing diease.

A dilation and curretage can be done.

Lung metastasis can occur.

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