Interleukin-4 (gene name)
Interleukin 4 (IL-4) is a cytokine released by CD4+ cells and is particularly important on resting and active B cells.
Expression
- cells that express: CD4+ cells (Th2 subtype)
- tissue distribution:
- temporal expression:
Function
- increases MHC II expression on macrophages and B cells
- induces B cell activation
- induces class switch to IgE if present alone
- decreases macrophage activity in combination with IL-10
Interactions and Signalling
- receptor:
Role in Disease
- if any
Structure
- template
Gene and Processing
- PubMed ref: here
- other info