Bradykinin (gene name)
Bradykinin is released during acute inflammation. It is a potent vasodilator and is also involved in the production of pain, possibly by acting directly on nerve endings.
Expression
- produced by liver?
- present in plasma as kininogen; cleaved by kallikrein following tissue injury and activation of Hageman factor
Function
- increases vascular permeability
- increases vasodilation
- causes pain
- induces smooth muscle contraction
Interactions and Signalling
- receptor:
Role in Disease
- if any
Structure
- template
Gene and Processing
- PubMed ref: here
- other info