Ras

Introduction to Ras

Ras is an important regulator of mitogenic signal transduction, acting to amplify signals to tell the cell to grow.

Ras Structure

Ras is a GTPase, becoming active after allostgeric activation of GTP.

Ras and Cancer

The importance of Ras is shown in its pathogemic role in perhaps 25% of human cancers, often at Gly-12.